Adrenal cancer, also known as adrenal cortex cancer, is a relatively rare malignant tumor originating from the adrenal cortex tissue. The malignancy of this disease is high, the disease develops rapidly, and the prognosis of patients is often poor. The following is an introduction to adrenal cancer and its latest treatment methods:
The clinical manifestations of adrenal cancer are diverse, which may include symptoms such as hypertension, abdominal masses, abdominal pain, metabolic abnormalities, etc. Because of its low incidence rate, early diagnosis is difficult, but early detection and timely treatment are essential to improve the survival rate of patients.
therapeutic method
Surgical treatment:
Surgical resection is the preferred method for treating adrenal cancer, especially for early-stage and adrenal limited tumors. Surgery should aim to completely remove the tumor and its surrounding adipose tissue, suspected invaded areas, and lymph nodes as much as possible. For cases of adjacent organ involvement, a complete resection should be performed to ensure a negative surgical margin.
Early stage adrenal cancer patients can generally achieve a high cure rate through radical surgical resection.
medication:
Mitotan: This is a drug that targets the mitochondria of adrenal cortex cells and can induce cell death. For patients with advanced adrenal cancer who are not suitable for surgery, the combination of mitoxan and platinum based chemotherapy can be used as a first-line treatment option. However, it should be noted that Mitotan may not have been listed domestically yet.
Targeted therapy: With the development of genomics and molecular biology, targeted therapy has become a new trend in the treatment of adrenal cancer. Inhibiting the growth and spread of cancer cells by specifically targeting certain key molecules in cancer cells. For example, targeted drugs such as insulin-like growth factor-1 receptor inhibitors and tyrosine kinase inhibitors are showing good efficacy in clinical trials.
Radiotherapy and chemotherapy:
The role of radiotherapy in the treatment of adrenal cancer is still controversial, but it may have certain therapeutic effects on patients in certain specific situations.
Although chemotherapy can kill tumor cells and reduce tumor size, its effect is not particularly ideal, especially for patients with advanced or metastatic adrenal cancer.
Immunotherapy:
Immunotherapy is a major breakthrough in the field of cancer treatment in recent years, which activates the patient's own immune system to attack and eliminate tumor cells. Multiple immunotherapy drugs have achieved significant therapeutic effects in clinical trials, providing new treatment options for patients with adrenal cancer.
summary
There are various treatment methods for adrenal cancer, including surgery, medication, radiation therapy, chemotherapy, and immunotherapy. The selection of treatment plan should be based on the specific condition of the patient, the staging and biological characteristics of the tumor. In addition, with the continuous deepening of medical research and advances in technology, it is believed that there will be more effective treatment methods in the future, bringing better treatment effects and quality of life to patients.
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